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George Wright Selected Research

6-(4-hydroxyphenylhydrazino)uracil

1/2019Discovery and development of DNA polymerase IIIC inhibitors to treat Gram-positive infections.

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George Wright Research Topics

Disease

15Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
01/2021 - 06/2002
11Neoplasms (Cancer)
01/2020 - 06/2002
6Lymphoma (Lymphomas)
05/2014 - 12/2008
5B-Cell Lymphoma (Lymphoma, B Cell)
02/2015 - 08/2005
3Burkitt Lymphoma (Burkitt's Lymphoma)
02/2015 - 10/2012
2Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated)
01/2018 - 05/2014
2Disease Progression
10/2013 - 06/2007
2Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
04/2007 - 12/2005
2Colorectal Neoplasms (Colorectal Cancer)
08/2006 - 08/2003
1Febrile Neutropenia
01/2021
1Anemia
01/2021
1Infections
01/2019
1Clostridium Infections
01/2019
1Extranodal NK-T-Cell Lymphoma
05/2014
1Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral)
05/2014
1T-Cell Lymphoma (Lymphoma, T Cell)
05/2014
1Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma)
05/2014
1Multiple Myeloma
08/2007
1Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
01/2007
1Neutropenia
08/2005
1Carcinogenesis
08/2003
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
06/2003
1X-Linked Combined Immunodeficiency Diseases (X Linked Severe Combined Immunodeficiency)
02/2003
1Mesenteric Ischemia
09/2002
1Ischemia
09/2002
1Ischemic Colitis
09/2002
1Hemorrhage
09/2002
1Abdominal Pain (Pain, Abdominal)
09/2002

Drug/Important Bio-Agent (IBA)

4Proteins (Proteins, Gene)FDA Link
01/2018 - 12/2005
4Biological ProductsIBA
05/2014 - 04/2006
4Rituximab (Mabthera)FDA Link
04/2013 - 08/2005
3Prednisone (Sone)FDA LinkGeneric
04/2013 - 08/2005
3Cyclophosphamide (Cytoxan)FDA LinkGeneric
04/2013 - 08/2005
3Vincristine (Oncovin)FDA LinkGeneric
04/2013 - 08/2005
3NF-kappa B (NF-kB)IBA
12/2008 - 08/2007
3Messenger RNA (mRNA)IBA
06/2007 - 02/2003
3Cyclin D1IBA
06/2007 - 02/2003
2Lenalidomide (CC 5013)FDA Link
01/2021 - 06/2012
2ibrutinibIBA
01/2021 - 08/2015
2DNA (Deoxyribonucleic Acid)IBA
01/2019 - 06/2002
2Transcription Factors (Transcription Factor)IBA
01/2018 - 02/2014
2Doxorubicin (Adriamycin)FDA LinkGeneric
04/2013 - 10/2012
2Etoposide (VP 16)FDA LinkGeneric
04/2013 - 08/2005
2RNA (Ribonucleic Acid)IBA
10/2012 - 08/2010
2CyclinsIBA
04/2007 - 12/2005
1GuanineIBA
01/2019
1Pharmaceutical PreparationsIBA
01/2019
1DNA-Directed DNA Polymerase (Polymerases, DNA)IBA
01/2019
1IbezapolstatIBA
01/2019
16-(4-hydroxyphenylhydrazino)uracilIBA
01/2019
1ChromatinIBA
01/2018
1MicroRNAs (MicroRNA)IBA
02/2015
1Anaplastic Lymphoma KinaseIBA
05/2014
1Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
02/2014
1AntigensIBA
02/2014
1Immunoglobulins (Immunoglobulin)IBA
02/2014
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
02/2014
1Transcription Factor 7-Like 1 ProteinIBA
02/2014
1MethyltransferasesIBA
10/2013
1Filgrastim (Neupogen)FDA Link
04/2013
1InterferonsIBA
06/2012
1ParaffinIBA
06/2011
1carboxyl radical (COO-)IBA
06/2011
1Formaldehyde (Formol)FDA Link
06/2011
1Phosphotransferases (Kinase)IBA
02/2011
1Immunoglobulin M (IgM)IBA
01/2010
1Bortezomib (Velcade)FDA Link
06/2009
1I-kappa B KinaseIBA
12/2008
1Interleukin-10 (Interleukin 10)IBA
04/2008
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
04/2008
1Interleukin-6 (Interleukin 6)IBA
04/2008
1RNA IsoformsIBA
06/2007
13' Untranslated Regions (3' UTR)IBA
06/2007
1acceleratory factor from growth hormone (AcG)IBA
08/2006
1Cyclin D2IBA
12/2005
1Cyclin D3IBA
12/2005
1Complementary DNA (cDNA)IBA
08/2003
1Calcibiotic Root Canal SealerIBA
08/2003
1Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA
06/2003
1interleukin-21 (interleukin 21)IBA
02/2003
1Interleukin-4 (Interleukin 4)IBA
02/2003
1Interleukin-9 (Interleukin 9)IBA
02/2003
1Interleukin-7 (Interleukin 7)IBA
02/2003
1InterleukinsIBA
02/2003
1Cytokine Receptors (Cytokine Receptor)IBA
02/2003
1Interleukin-15 (Interleukin 15)IBA
02/2003
1CytokinesIBA
02/2003
1PapaverineIBA
09/2002
1Cocaine (Cocaine HCl)IBA
09/2002

Therapy/Procedure

6Therapeutics
10/2013 - 02/2003
5Drug Therapy (Chemotherapy)
10/2012 - 06/2002
1Immunotherapy
01/2020
1Radiotherapy
04/2013